Figure 1.

Clinical investigation and rotarod testing of TMEV- and mock-infected SJL mice. TMEV-infected mice showed significant clinical signs starting at 91 dpi (A) and a deterioration of motor coordination starting at 63 dpi (B) compared to mock infected animals. Graphs display mean and standard error of mean. Significant differences between the groups as detected by two-way repeated measure ANOVA with post-hoc independent t-tests for the different time points are marked by asterisks (* p ≤ 0.05).