Table 8.
Cytotoxic activity of the anthocyanins rich extract obtained under optimal extraction conditions (mean ± SD).
| Tumor Cell Lines | Concentrations (GI50 Values, µg/mL) |
|---|---|
| MCF-7 (breast carcinoma) | >400 |
| NCI-H460 (lung carcinoma) | >400 |
| HeLa (cervical carcinoma) | 213 ± 9 |
| HepG2 (hepatocellular carcinoma) | 198 ± 9 |
| Non-Tumour Cells | |
| PLP2 (non-tumor porcine liver primary cells) | >400 |
GI50 values - concentration that inhibited 50% of cell growth. Ellipticin GI50 (positive control): 1.21 μg/mL (MCF-7), 1.03 μg/mL (NCI-H460), 0.91 μg/mL (HeLa), 1.10 μg/mL HepG2) and 2.29 μg/mL (PLP2).