Table 4.
Summary of the main specific differential chromosomal regions between each age-of-onset group, for each colon location.
| Chromosomal Segment |
RIGHT-SIDED | LEFT-SIDED COLON | RECTUM | |||||
| EO (n = 13) | LO (n = 35) | EO (n = 27) | LO (n = 19) | EO (n =2 0) | LO (n = 32) | |||
| % | % | % | % | % | % | |||
| chr1 | p32.3-22.2 | 0 | 51 | |||||
| chr1 | p21.3-11.2 | 0 | 51 | |||||
| chr2 | p25.2 | 0 | 51 | RIGHT COLON | ||||
| chr2 | p11.2 | 54 | 20 | |||||
| chr10 | q11.21-11.22 | 70 | 23 | |||||
| chr14 | q11.1-11.2 | 85 | 37 | |||||
| chr16 | p13.12-13.11 | 54 | 11 | |||||
| chr17 | p11.2 | 62 | 29 | |||||
| chr18 | p11.32-11.21 | 0 | 54 | |||||
| chr18 | q21.1-21.1 | 8 | 51 | |||||
| chr18 | q21.31-21.33 | 8 | 54 | |||||
| chr7 | q11.22-21.11 | 15 | 63 | |||||
| chr7 | q22.1-31.33 | 15 | 57 | |||||
| chr7 | p12.2-11.2 | 15 | 54 | |||||
| chr7 | q11.21 | 15 | 54 | |||||
| chr9 | q12-13 | 0 | 51 | |||||
| chr9 | q33.3 | 62 | 29 | |||||
| chr9 | q34.12-34.13 | 62 | 29 | |||||
| chr13 | q11 | 8 | 51 | |||||
| chr21 | q22.3 | 62 | 26 | |||||
| chr1 | p12-q21.1 | 63 | 10 | LEFT COLON | ||||
| chr5 | q13.1-13.2 | 67 | 16 | |||||
| chr9 | p12-q24.22 | 59 | 21 | |||||
| chr9 | q31.3-33.1 | 52 | 16 | |||||
| chr11 | p11.12-q12.1 | 63 | 21 | |||||
| chr11 | q14.1-14.3 | 59 | 21 | |||||
| chr15 | p11.1-q11.2 | 0 | 26 | |||||
| chr19 | p13.12-12 | 59 | 26 | |||||
| chr1 | p36.32-36.13 | 5 | 41 | RECTUM | ||||
| chr1 | p36.23-36.22 | 37 | 12 | |||||
| chr3 | p21.31-21.1 | 42 | 32 | |||||
| chr5 | q13.2 | 5 | 53 | |||||
EO: Early-onset; LO: Late-onset; Chr: chromosome; Green: gained regions; Red: lost regions. Percentages shown in bold indicate frequencies that are at least twice as high in one age-of-onset group as in the other.