Table 3.
Plasma lipids, cholesterol: phospholipid and cholesterol: HDL-cholesterol ratio and atherogenic index of animals fed the experimental diets.
| ANOVA | ||||
|---|---|---|---|---|
| ED | D | DE | p | |
| Glycemia 3rd week (mmol/L) | 8.02 ± 0.57 | 8.04 ± 0.96 | 8.27 ± 0.70 | p > 0.05 |
| Glycemia 8th week (mmol/L) | 15.76 ± 0.76 b | 18.11 ± 1.65 c | 13.94 ± 1.13 a | p < 0.001 |
| Total cholesterol (mmol/L) | 2.26 ± 0.12 a | 2.95 ± 0.22 c | 2.57 ± 0.16 b | p < 0.001 |
| Triglycerides (mmol/L) | 0.74 ± 0.05 a | 0.87 ± 0.11 b | 0.71 ± 0.13 ab | p = 0.013 |
| Phospholipids (mmol/L) | 1.14 ± 0.13 | 1.28 ± 0.09 | 1.26 ± 0.17 | p > 0.05 |
| Total lipids (mg/dL) * | 235 ± 14.1 a | 282 ± 29.8 b | 252 ± 24.6 ab | p = 0.003 |
| Cholesterol:phospholipids (mol/mol) | 1.01 ± 0.09 | 1.13 ± 0.10 | 1.02 ± 0.16 | p > 0.05 |
| Cholesterol:HDL cholesterol (mol/mol) | 1.65 ± 0.29 a | 2.37 ± 0.45 b | 2.10 ± 0.18 b | p < 0.001 |
| Atherogenic index ** | 0.65 ± 0.29 a | 1.37 ± 0.45 b | 1.10 ± 0.18 b | p < 0.001 |
Results are means ± SD (n = 8). Labeled means in a row without a common letter differ (p < 0.05; a < b < c; ab = a or b; ANOVA followed by the Bonferroni or T2 Tamhane post hoc test). ED: rats fed the CFE-diet since the beginning of the study; D: rats fed the Chol-diet; DE: rats fed the CFE-diet when the diabetic state was confirmed. For more abbreviations see footnotes of Table 1. * Total lipids: cholesterol + triglycerides + phospholipids; ** Atherogenic index = (total cholesterol–HDL cholesterol)/HDL cholesterol. To transform mmol/L into mg/dL of cholesterol, triglycerides, and phospholipids, multiply data by 38.68, 89.0, and 75.0, respectively.