Table 2.
Maternal and infant vitamin B12 and folate status.
| Maternal | Infant | ||||||
|---|---|---|---|---|---|---|---|
| Mid-Gestation | Delivery | Cord Blood | |||||
| Variables a | Total | Total | Recruited at Mid-Gestation |
Recruited at Delivery | Total | Mothers Recruited at Mid-Gestation | Mothers Recruited at Delivery |
| n | 124 | 131 | 75 | 56 | 89 | 58 | 31 |
| Serum vitamin B12, pmol/L | 343.7 (237.8, 400.7) | 216.2 (161.6, 297.8) | 216.2 (173.4, 311.8) | 211.2 (158.7, 267.0) | 597.0 (471.6, 796.3) | 569.4 (478.6, 844.3) | 602.9 (406.6, 722.1) |
| <148.0 pmol/L | 1.6 (2) | 15.3 (20) | 14.7 (11) | 16.1 (9) | 0.0 (0) | 0.0 (0) | 0.0 (0) |
| ≥148 to <221.0 pmol/L | 21.0 (26) | 38.2 (50) | 37.3 (28) | 39.3 (22) | 2.3 (2) | 0.0 (0) | 6.5 (2) |
| ≥221 pmol/L | 77.4 (96) | 46.6 (61) | 48.0 (36) | 44.6 (25) | 99.8 (87) | 100.0 (58) | 93.5 (29) |
| n | 122 | 130 | 74 | 56 | 86 | 55 | 31 |
| Serum folate, nmol/L | 39.3 (31.7, 50.5) | 39.7 (31.8, 50.4) | 42.8 (32.2, 51.4) | 37.7 (28.8, 48.4) | 66.7 (53.1, 85.5) | 66.3 (52.1, 84.4) | 67.7 (55.5, 98.4) |
| ≤29.45b nmol/L | 19.7 (24) | 20.0 (26) | 13.5 (10) | 28.6 (16) | 2.3 (2) | 3.6 (2) | 0.0 (0) |
| >29.45, ≤35.79 nmol/L | 20.5 (25) | 16.9 (22) | 18.9 (14) | 14.3 (8) | 2.3 (2) | 3.6 (2) | 0.0 (0) |
| >35.79, ≤43.94 nmol/L | 19.7 (24) | 20.0 (26) | 17.6 (13) | 23.2 (13) | 4.7 (4) | 5.5 (3) | 3.2 (1) |
| >43.94, ≤52.66 nmol/L | 19.7 (24) | 22.3 (29) | 29.7 (22) | 12.5 (7) | 14.0 (12) | 12.7 (7) | 16.1 (5) |
| >52.66 nmol/L | 20.5 (25) | 20.8 (27) | 20.3 (15) | 21.4 (12) | 76.7 (66) | 74.6 (41) | 80.7 (25) |
a Values are median and interquartile range (IQR) and (%) n. b Note: No values of serum folate were <6.8 nmol/L; the cut-offs presented for serum folate are quintiles based on the distribution of serum folate concentrations at mid-gestation.