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. 2019 Feb 17;24(4):720. doi: 10.3390/molecules24040720

Figure 4.

Figure 4

Inhibition of [D-Arg1, D-Phe5, D-Trp7,9, Leu11]-substance P (GHSR antagonist) on stimulatory effects of GH secretion by GHRP-6 and echinacoside treatment. Rat primary anterior pituitary cells were incubated with GHRP-6 (10−7 M) and echinacoside (10−5 M) in the presence and absence of [D-Arg1, D-Phe5, D-Trp7,9, Leu11]-substance P (0.5 μM) for 15 min. Data were presented as means ± SD with n = 6. Significance levels seen by T Test were * p < 0.05 versus the control, # p < 0.05 and ## p < 0.005 significant differences between columns.