Table 2.
Association between XPG rs17655 G > C polymorphism and colorectal cancer risk
| Genotype | Cases | Controls | P a | OR (95% CI) | P | AOR (95% CI)b | P b | ||
|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||
| No. | % | No. | % | ||||||
| rs17655 (HWE = 0.854) | |||||||||
| GG | 248 | 24.34 | 265 | 25.58 | 1.00 | 1.00 | |||
| CG | 510 | 50.05 | 515 | 49.71 | 1.06 (0.86-1.31) | 0.601 | 0.99 (0.79-1.24) | 0.947 | |
| CC | 261 | 25.61 | 256 | 24.71 | 1.09 (0.85-1.39) | 0.492 | 1.10 (0.85-1.43) | 0.461 | |
| Additive | 0.781 | 1.04 (0.92-1.18) | 0.493 | 1.05 (0.92-1.20) | 0.459 | ||||
| Dominant | 771 | 75.66 | 771 | 74.42 | 0.515 | 1.07 (0.88-1.31) | 0.516 | 1.03 (0.83-1.27) | 0.797 |
| Recessive | 758 | 74.39 | 780 | 75.29 | 0.637 | 1.05 (0.86-1.28) | 0.637 | 1.11 (0.90-1.37) | 0.342 |
OR, odds ratio; CI, confidence interval; AOR, adjusted odds ratio; HWE, Hardy-Weinberg equilibrium.
a
Chi-square test for genotype distributions between patients and controls.
b
Adjusted for age, gender, BMI, smoking and drinking status.