Table 4.

Main characteristics of included studies for the final meta-analysis

Name	Year	Region	Ethnicity	Design	Genotype	Case				Control				MAF	HWE
					Method	GG	CG	CC	All	GG	CG	CC	All
Bigler	2005	USA	Caucasian	PB	Taqman	440	237	36	713	353	226	37	616	0.24	0.917
Huang	2006	USA	Caucasian	PB	Sequencing	407	243	29	679	403	265	29	697	0.23	0.073
Pardini	2008	Czech	Caucasian	HB	PCR-RFLP	334	177	21	532	356	153	23	532	0.19	0.211
Joshi	2009	USA	Caucasian	FB	Taqman	183	114	11	308	213	137	11	361	0.22	0.046
Canbay	2011	Turkey	Caucasian	PB	PCR-RFLP	43	34	2	79	148	83	16	247	0.23	0.352
Gil	2012	Poland	Caucasian	PB	PCR-RFLP	86	35	11	132	64	31	5	100	0.21	0.625
Liu	2012	China	Asian	HB	PCR-RFLP	233	603	192	1028	329	537	219	1085	0.45	0.996
Du	2014	China	Asian	HB	TaqMan	286	459	133	878	355	405	124	884	0.37	0.623
Steck	2014	USA	Caucasian	PB	MassARRAY	183	100	15	298	335	170	27	532	0.21	0.372
Steck	2014	USA	African	PB	MassARRAY	65	120	39	224	100	151	66	317	0.45	0.519
Paszkowska-Szczur	2015	Poland	Caucasian	HB	Taqman	429	272	32	733	869	404	85	1358	0.21	0.0001
Sun	2015	China	Asian	HB	PCR-RFLP	216	476	198	890	227	497	186	910	0.48	0.004
Kabzinski	2015	Poland	Caucasian	HB	QPCR	36	171	27	234	43	175	20	238	0.45	< 0.001
Su	Current	China	Asian	HB	Taqman	248	510	261	1019	265	515	256	1036	0.50	0.854

MAF, minor allele frequency; HWE, Hardy-Weinberg equilibrium; PB, population based; HB, hospital based; FB, family based; PCR-RFLP, polymerase chain reaction-restriction fragment length polymorphism.