Figure 1.

Acute kidney injury in rats induced by ischemia and reperfusion. A. The levels of urea (left) and creatinine (right) in plasma of rats that underwent ischemia and reperfusion treatment. The control group and the sham group were used as controls. B. Structural alteration of rat renal tubules induced by ischemia and reperfusion treatment. The histological properties were observed under a microscope following hematoxylin and eosin staining. C. Apoptosis of rat kidney cells during kidney injury induced by ischemia and reperfusion. Cell apoptosis was evaluated using the TUNEL method. I/R: ischemia and reperfusion. *, P < 0.05, **, P < 0.01.