Figure 5.

Overexpression of YAP abrogated NC-mediated inhibition of migration and invasion. Left panel: Cell migration and invasion were measured using Transwell chambers assay in prostate cancer cells after NC treatment or YAP cDNA transfection or combinations. Right panel: Quantitative results were illustrated for left panel. Control: pcDNA3.1; NC: 3 μM (DU145), 10 μM (PC-3) NC; YAP: YAP cDNA vector; Both: YAP cDNA+NC. *P<0.01, compared with control; ^#P<0.05, compared with NC treatment alone or YAP cDNA transfection alone.