Fig. 2.

Efficacy of the age correction procedure following Dukart et al. (2011). Z-maps showing the results of correlation analyses in the patient cohort between age and gray matter density maps before (upper row) and after (bottom row) the applied age-correction procedure. The pattern of negative correlations between age and gray matter density, mainly seen in medial temporal and medial frontal structures, is suppressed after age correction. Images shown in neurological orientation: left of the brain corresponds to the left of the image.