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. 2019 Feb 26;2019:1678193. doi: 10.1155/2019/1678193

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Copyright © 2019 Amanda E. Kahn et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Pathology of lesion following partial nephrectomy. (a) Pathology of lesion showing area with prominent hemosiderin laden macrophages and multinucleate giant cells (H/E, 20X). Lower inset demonstrating foci of giant cells associated with cholesterol clefts (arrow) (H/E, 20X). Upper inset shows necrotic fat (arrow) with surrounding inflammatory reaction (H/E, 4X). (b) CD68 (KP1) immunohistochemistry (10X). CD68 is highly expressed by monocytes, macrophages, and histiocytes and is positive in numerous histiocytes and macrophages in adipose tissue. (c) Immunohistochemistry demonstrating a negative study for cytokeratin AE1/AE3 confirming no recurrence of renal cell carcinoma (10X). (d) Immunohistochemistry demonstrating a negative study for PAX-8 confirming no recurrence of renal cell carcinoma (10X).