Figure 11.

Effect of various doses of OA extract on the expressions of TNF-α in the hippocampus. (a) Representative western blot showing the levels of TNF-α. (b) Relative density of TNF-α. Data are presented as mean ± SEM (n = 6/group). ^aaaP value <0.001, compared to naïve intact rats; ^bbbP value <0.001, compared to sham operation which received HCHF diet and vehicle; and ^∗∗∗P value < 0.001, compared to MCAO rats which received HCHF and vehicle. HCHF: high-carbohydrate high-fat diet; MCAO: right middle cerebral artery occlusion; OA1, OA2, and OA3: the combined extract of O. sativa and A. graveolens at doses of 0.5, 5, and 50 mg/kg BW, respectively.