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. 2019 Mar 5;10:175. doi: 10.3389/fgene.2019.00175

Table 1.

Genotype frequencies, HWE tests, and single-SNP association analyses of 30 RELN SNPs in the SZ and control cases.

dbSNP ID Allele (D/d)a Case
Control
Genotype (p)e Allele (P)e
nb HWE (p)c Genotype
MAFd nb HWE (p)c Genotype
MAFd
DD Dd dd DD Dd dd
rs11764507 G/A 100 0.068 72 22 6 0.170 161 0.381 106 52 3 0.180 0.062 0.768
rs17157643 T/A 100 1.000 78 21 1 0.115 162 0.734 137 25 0 0.077 0.213 0.145
rs6465938 C/T 100 0.046 40 38 22 0.410 163 0.388 60 83 20 0.377 0.048 0.455
rs39339 A/C 100 0.416 77 20 3 0.130 162 0.714 126 35 1 0.114 0.283 0.589
rs155333 G/A 100 0.123 54 34 12 0.290 162 0.546 78 72 12 0.296 0.201 0.878
rs262355 T/A 99 0.071 55 32 12 0.283 162 0.700 80 70 12 0.290 0.173 0.858
rs1510846 T/C 95 0.834 29 49 17 0.437 162 0.210 50 72 40 0.469 0.408 0.478
rs11496125 C/T 98 1.000 36 47 15 0.393 162 0.447 65 71 26 0.380 0.850 0.764
rs10435342 C/T 100 0.277 85 13 2 0.085 163 0.995 143 19 1 0.064 0.599 0.376
rs661575 C/T 99 0.131 51 34 14 0.308 163 0.072 81 60 22 0.319 0.958 0.794
rs607755 A/G 99 1.000 37 47 15 0.389 160 0.182 47 88 25 0.431 0.429 0.342
rs563264 A/G 100 1.000 95 5 0 0.025 162 0.443 150 11 1 0.040 0.386 0.356
rs540058 T/C 98 1.000 93 5 0 0.026 161 0.446 149 11 1 0.040 0.404 0.370
rs727708 A/G 100 0.943 30 51 19 0.445 160 1.000 36 80 44 0.475 0.184 0.076
rs12705141 A/T 100 0.664 74 23 3 0.145 161 0.747 110 45 6 0.177 0.528 0.338
rs2299356 A/G 100 0.406 34 53 13 0.395 161 0.880 47 82 32 0.453 0.344 0.190
rs362691f G/C 100 1.000 84 15 1 0.085 163 1.000 121 39 3 0.138 0.153 0.067
rs123714 C/T 100 0.763 52 40 10 0.300 163 0.614 91 64 8 0.245 0.247 0.169
rs123713 C/T 100 0.763 50 40 10 0.300 161 0.899 90 62 9 0.248 0.339 0.196
rs144525 A/G 99 0.536 69 29 1 0.157 161 0.380 101 56 4 0.199 0.448 0.227
rs362626 C/A 100 1.000 40 46 14 0.370 161 0.307 61 82 18 0.366 0.628 0.935
rs362814 A/T 99 0.613 41 43 15 0.369 161 0.497 62 80 19 0.366 0.521 0.959
rs362813 T/C 100 0.961 26 49 25 0.495 163 0.694 47 78 38 0.472 0.857 0.614
rs362731 T/C 100 1.000 26 50 24 0.490 162 0.759 47 78 37 0.469 0.856 0.642
rs362726 T/C 98 0.879 24 51 23 0.495 163 1.000 56 79 28 0.414 0.189 0.072
rs2535764 C/T 99 0.066 68 24 7 0.192 163 0.352 106 48 9 0.202 0.647 0.769
rs362719 C/A 100 0.926 36 47 17 0.405 159 0.131 74 62 23 0.340 0.258 0.132
rs2299334 G/A 100 0.680 66 32 2 0.180 163 1.000 104 52 7 0.202 0.612 0.527
rs11976900 A/G 99 0.486 57 34 8 0.253 161 0.139 92 54 15 0.261 0.951 0.833
rs2229864f C/T 100 1.000 68 29 3 0.175 161 0.214 104 47 10 0.208 0.545 0.354

aMajor/minor allele, major, and minor alleles are denoted by D and d, respectively. bNumbers of samples that are successfully genotyped in patients and controls, respectively. cp-Values of the Hardy-Weinberg equilibrium (HWE) tests from Haploview v4.2. dThe minor allele frequency of 30 selected SNPs in this study. eUncorrected p-values of allelic and genotypic association analysis in this study. fTwo exonic SNPs selected in this report.