Fig. 4.

Increased grey matter density in SMA patients described by voxel-based-morphometry.

(A) Increased grey matter density in SMA patients compared to healthy controls at p < .05 FWE (TFCE, age and gender corrections) identified by VBM. MNI coordinates are provided for the relevant axial, sagittal and coronal views. (B) Region of interest (ROI) morphometry in the motor cortex (yellow) highlights a focus of increased grey matter density in SMA patients compared to controls at p < .05 FWE TFCE. MNI coordinates of the focus (red) are indicated on the right bottom corner of the figure. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)