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. 2019 Jan 30;40:394–405. doi: 10.1016/j.ebiom.2019.01.037
% per cent
μm micrometer
μM micromolar
5-FU 5-fluorouracil
AMP adenosine monophosphate
AMPK AMP-activated protein kinase
CAFs cancer-associated fibroblasts
CC3 cleaved caspase-3
CDA cytidine deaminase
CM conditioned medium
d0 day 0
DAPI 4′,6-diamidino-2-phenylindole
dCK deoxycytidine kinase
DCTD deoxycytidylate deaminase
dFdC 2′,2′-difluoro-2′-deoxycytidine
dFdCMP 2′,2′-difluoro-2′-deoxycytidine monophosphate
dFdCDP 2′,2′-difluoro-2′-deoxycytidine diphosphate
dFdCTP 2′,2′-difluoro-2′-deoxycytidine triphosphate
dFdU 2′,2′-difluoro-2′-deoxyuridine
DMEM Dulbecco's Modified Eagle Medium
DNA deoxyribonucleic acid
FBS fetal bovine serum
g gram(s)
h hour(s)
H&E hematoxylin and eosin
HA-tag hemagglutinin tag
hEnt human equilibrative nucleoside transporter
HRP horseradish peroxidase
HSP90 heat shock protein 90
ICC immunocytochemistry
IHC immunohistochemistry
IgG immunoglobulin G
kg kilogram
KPC LSL-KrasG12D/+;LSL-Trp53R172H/+;Pdx-1-Cre
LC-MS/MS liquid chromatography tandem mass-spectrometry
MEM Minimum Essential Media
mg milligrams
M-MLV Moloney Murine Leukemia Virus
mRNA messenger ribonucleic acid
MTT 3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide
nM nanomolar
ns non-significant
NT5 5′-nucleotidase
NT5C1A cytosolic 5′-nucleotidase 1A
PBS phosphate buffered saline
PDAC pancreatic ductal adenocarcinoma
pM picomolar
PSCs pancreatic stellate cells
qRT-PCR quantitative real-time polymerase chain reaction
RRM1 ribonucleotide reductase M1
SEM standard error of mean
TAM tumor-associated macrophages
TMA tissue microarray
TME tumor microenvironment
U.S. United States
WB Western blot