% |
per cent |
μm |
micrometer |
μM |
micromolar |
5-FU |
5-fluorouracil |
AMP |
adenosine monophosphate |
AMPK |
AMP-activated protein kinase |
CAFs |
cancer-associated fibroblasts |
CC3 |
cleaved caspase-3 |
CDA |
cytidine deaminase |
CM |
conditioned medium |
d0 |
day 0 |
DAPI |
4′,6-diamidino-2-phenylindole |
dCK |
deoxycytidine kinase |
DCTD |
deoxycytidylate deaminase |
dFdC |
2′,2′-difluoro-2′-deoxycytidine |
dFdCMP |
2′,2′-difluoro-2′-deoxycytidine monophosphate |
dFdCDP |
2′,2′-difluoro-2′-deoxycytidine diphosphate |
dFdCTP |
2′,2′-difluoro-2′-deoxycytidine triphosphate |
dFdU |
2′,2′-difluoro-2′-deoxyuridine |
DMEM |
Dulbecco's Modified Eagle Medium |
DNA |
deoxyribonucleic acid |
FBS |
fetal bovine serum |
g |
gram(s) |
h |
hour(s) |
H&E |
hematoxylin and eosin |
HA-tag |
hemagglutinin tag |
hEnt |
human equilibrative nucleoside transporter |
HRP |
horseradish peroxidase |
HSP90 |
heat shock protein 90 |
ICC |
immunocytochemistry |
IHC |
immunohistochemistry |
IgG |
immunoglobulin G |
kg |
kilogram |
KPC |
LSL-KrasG12D/+;LSL-Trp53R172H/+;Pdx-1-Cre |
LC-MS/MS |
liquid chromatography tandem mass-spectrometry |
MEM |
Minimum Essential Media |
mg |
milligrams |
M-MLV |
Moloney Murine Leukemia Virus |
mRNA |
messenger ribonucleic acid |
MTT |
3-(4,5-Dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide |
nM |
nanomolar |
ns |
non-significant |
NT5 |
5′-nucleotidase |
NT5C1A |
cytosolic 5′-nucleotidase 1A |
PBS |
phosphate buffered saline |
PDAC |
pancreatic ductal adenocarcinoma |
pM |
picomolar |
PSCs |
pancreatic stellate cells |
qRT-PCR |
quantitative real-time polymerase chain reaction |
RRM1 |
ribonucleotide reductase M1 |
SEM |
standard error of mean |
TAM |
tumor-associated macrophages |
TMA |
tissue microarray |
TME |
tumor microenvironment |
U.S. |
United States |
WB |
Western blot |