Table 5.

MAGeT-derived brain volumes.

Group by time point 2 (16 weeks)			Group by time point 3 (24 weeks)
Structure	beta	t-value	Structure	beta	t-value
Cingulate region (bilateral)	L 1.85 R 2.05	L 3.78 R 3.74	Cingulate region (bilateral)	L − 1.54 R − 1.82	L − 3.21 R − 3.39
Frontal region (left)	3.59	3.24	Frontal region (left)	−3.94	−3.60
Hippocampal region (bilateral)	L 2.73 R 2.77	L 3.26 R 3.54	Hippocampal region (left)	−2.11	−3.57
Parietal region (right)	4.62	3.50	Parietal region (bilateral)	L − 4.78 R − 5.21	L − 3.00 R − 4.12
Olfactory bulbs (bilateral)	L 2.80 R 3.05	L 2.85 R 3.04	Olfactory bulbs (bilateral)	L − 2.57 R − 2.79	L − 2.85 R − 3.12
Occipital region (bilateral)	L 2.00 R 2.55	L 3.34 R 4.30	Occipital region (left)	−2.03	−3.46
Midbrain (bilateral)	3.09	3.45	Midbrain (bilateral)	−2.62	−2.96
Amygdala (right)	2.01	3.99	Amygdala (left)	−1.88	−3.75
Lateral septum (bilateral)	L 0.57 R 0.47	L 3.14 R 3.27	Fimbria (bilateral)	L − 0.52 R − 0.57	L − 3.00 R − 3.46
Olfactory tubercle (bilateral)	L 0.53 R 0.49	L 3.07 R 2.98	Temporal region (left)	−1.38	−3.00
Entorhinal cortex (left)	2.17	4.21	Nucleus accumbens (left)	−0.65	−2.95
Thalamus (right)	2.19	2.97	Hypothalamus (right)	−1.12	−3.37
Cerebellar white matter (left)	−0.40	−3.22	Subiculum (left)	−0.55	−3.13
Corticospinal tract / pyramids (right)	0.34	3.18	Insular region (right)	−2.55	−4.94
Inferior olivary complex (right)	0.17	2.83	Basal forebrain (left)	−0.81	−4.41
Insular claustrum (right)	0.46	3.46	Stria terminalis (right)	−0.24	−4.53
			Lateral olfactory tract (bilateral)	L − 0.51 R − 0.33	L − 4.13 R − 3.19
			Endopiriform claustrum (right)	−0.42	−3.22
			Anterior commissure: pars anterior (bilateral)	L − 0.40 R − 0.30	L − 3.68 R − 3.06
			Superior olivary complex (right)	−0.21	−2.82
			Piriform cortex area (right)	−2.20	−3.89

Regions showing significant interaction for group by time point (FDR < 5%).