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. Author manuscript; available in PMC: 2019 Sep 4.
Published in final edited form as: Mol Pharm. 2018 Aug 13;15(9):3881–3891. doi: 10.1021/acs.molpharmaceut.8b00355

Figure 9. Influence of PEG-Peptide Size on Scavenger Receptor Inhibition.

Figure 9.

The percent of 125I-PEG-peptide recovered from the liver at a biodistribution time of 5 min following i.v. administration of triplicate mice under dose escalation of 1–80 nmol is illustrated. The IC50 values of 20–30 μM were derived from fitting the results with R2 =0.58 and 0.6 for panels A and D. A value of p < 0.05 was determined for PEG-peptides 35 and 38 when comparing 1 and 80 nmol dose.