Supplementary Table 5.
Diagnostic accuracy of reproductive hormones and testicular volume for the retrieval outcomes of haploid gamete in patients who underwent microdissection testicular sperm extraction
| AUC (95% CI) | Cutoff value | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | |
|---|---|---|---|---|---|---|
| INHB (pg ml−1) | 0.84 (0.75–0.91)a | >43.40 | 76.47 | 87.80 | 86.24 | 78.86 |
| FSH (IU l−1) | 0.80 (0.70–0.88)b | ≤6.75 | 72.55 | 92.68 | 90.84 | 77.15 |
| LH (IU l−1) | 0.76 (0.66–0.85)c | ≤4.97 | 54.90 | 90.24 | 84.91 | 66.68 |
| T (ng dl−1) | 0.58 (0.47–0.68)d | >399.50 | 49.02 | 70.73 | 62.61 | 58.11 |
| Testicular volume (ml) | 0.74 (0.64–0.83) | >11.00 | 92.16 | 48.78 | 64.28 | 86.15 |
aP<0.05: INHB versus T, INHB versus testicular volume; bP<0.05: FSH versus T; cP<0.05: LH versus T; dP<0.05: T versus testicular volume. micro-TESE: microdissection testicular sperm extraction; AUC: area under the curve; PPV: positive predictive value; NPV: negative predictive value; INHB: inhibin B; FSH: follicle-stimulating hormone; LH: luteinizing hormone; T: testosterone; CI: confidence interval