Figure 1.

Dose‐dependent recovery by phenolic compounds of age‐related hypertrophy observed by echocardiography. Left ventricular chamber and cardiac performance were over 14 months with or without PC or DMSO. Results are expressed as mean ± SEM. (a) LVIDd, (b) LVPWd, (c) IVSTd, (d) EF, and (e) FS. For SHAM‐DMSO rats: n = 6/group, and treated rats with PC: n = 8/group. #p < 0.05, time effect within each group (Month 14 vs. Month 1). *p < 0.05, effect of treatment after 14 months vs. SHAM and DMSO). PC 2.5 = phenolic compounds at 2.5 mg kg⁻¹ day⁻¹; PC 5 = phenolic compounds at 5 mg kg⁻¹ day⁻¹; PC 10 = phenolic compounds at 10 mg kg⁻¹ day⁻¹; PC 20 = phenolic compounds at 20 mg kg⁻¹ day⁻¹