Table 2.
ICA incidence and seizure characteristics.
| Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|
| ICA– | ICA+ | p | RR (95% CI) | p | |
| Sex | 0.171 | 0.87 (0.64–1.18) | 0.383 | ||
| Male | 129 | 91 | |||
| Female | 178 | 89 | |||
| Age at study (y.o) | 38.2 ± 14.9 | 44.5 ± 15.3 | 0.004 | – | – |
| Age at epilepsy onset (y) | 18.7 ± 16.4 | 28 ± 17.1 | <0.001 | 1.01 (1.00–1.02) | 0.222 |
| Epilepsy duration (y) | 19.5 ± 14.1 | 16.6 ± 14.1 | 0.077 | 0.98 (0.97–1.00) | 0.608 |
| Epilepsy type | – | – | – | ||
| Generalized | 51 | 0 | |||
| Focal | 251 | 180 | |||
| Epileptogenic zone | 0.002 | 0.58 (0.37–0.90) | 0.015 | ||
| Extratemporal | 133 | 40 | |||
| Temporal | 118 | 140 | |||
| Lateralization | 0.215 | – | – | ||
| Left | 90 | 94 | |||
| Right | 99 | 52 | |||
| State | 0.013 | 1.33 (1.08–1.64) | 0.008 | ||
| Awake | 191 | 92 | |||
| Asleep | 116 | 87 | |||
| Semiology | |||||
| GCS | 101 | 65 | 0.960 | – | – |
| NCS | 206 | 115 | |||
| PGESa | 0.308 | – | – | ||
| No | 90 | 12 | |||
| Yes | 70 | 53 | |||
| PGES durationa (s) | 36.3 ± 15.8 | 43.3 ± 29.7 | 0.618 | – | – |
| EEG recovery duration (s) | 70.9 ± 61.8 | 106.2 ± 162.1 | 0.512 | – | – |
| Recovery time to mild hypoxemiaa (s) | 41.8 ± 31.9 | 48.5 ± 46 | 0.903 | – | – |
| Total hypoxemia durationa (s) | 147.5 ± 70.4 | 149.9 ± 56.2 | 0.953 | – | – |
| SpO2 nadira (%) | 59.5 ± 14.4 | 58.3 ± 13.2 | 0.576 | – | – |
| PCCAa | 0.785 | – | – | ||
| No | 79 | 49 | |||
| Yes | 18 | 14 | |||
| PCCA durationa (s) | 8 ± 3.3 | 10.4 ± 6.7 | 0.509 | – | – |
GCS, generalized convulsive seizures; NCS, non-convulsive seizures; PCCA, post-convulsive central apnea; PGES, post-ictal generalized electroencephalographic suppression; SpO2, peripheral capillary oxygen saturation; y, years y.o, years old.
a
Analyzed only in GCS.