Table 3.
PCCA incidence and seizure characteristics.
| Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|
| PCCA – | PCCA + | p | RR (95% CI) | p | |
| Sex | 0.004 | 11.29 (4.5–28.34) | <0.001 | ||
| Male | 103 | 10 | |||
| Female | 84 | 31 | |||
| Age at study (yo) | 37.7 ± 13.7 | 34.6 ± 14 | 0.267 | – | – |
| Age at epilepsy onset | 20.2 ± 17.2 | 19.5 ± 10.7 | 0.774 | – | – |
| Epilepsy duration (y) | 17.4 ± 12.1 | 14.9 ± 11.9 | 0.323 | – | – |
| Epilepsy type | 0.016 | – | – | ||
| Generalized | 25 | 11 | |||
| Focal | 160 | 27 | |||
| Epileptogenic zone | 0.020 | 4.48 (1.02–19.59) | 0.046 | ||
| Extratemporal | 64 | 18 | |||
| Temporal | 96 | 9 | |||
| Lateralization | 0.148 | – | – | ||
| Left | 63 | 14 | |||
| Right | 52 | 4 | |||
| State | 0.738 | – | – | ||
| Awake | 97 | 20 | |||
| Asleep | 90 | 20 | |||
| ICA duration | 11.96 ± 5.75 | 18.6 ± 11.5 | 0.001 | 1.14 (1.05–1.25) | 0.001 |
| PGESa | 0.091 | 0.27 (0.16–0.47) | <0.001 | ||
| No | 60 | 8 | |||
| Yes | 126 | 33 | |||
| PGES durationa(s) | 38.7 ± 18.9 | 39.5 ± 27.8 | 0.804 | – | – |
| EEG recovery durationa (s) | 86.4 ± 80 | 83.5 ± 184.4 | 0.876 | – | – |
| Recovery time to mild hypoxemiaa (s) | 36.2 ± 31.3 | 58.3 ± 42 | 0.003 | – | – |
| Total hypoxemia durationa (s) | 144.86 ± 70.3 | 139.1 ± 40.9 | 0.301 | – | – |
| SpO2 nadira | 60.76 ± 13.8 | 58.3 ± 16 | 0.555 | – | – |
GCS, generalized convulsive seizures; ICA, ictal central apnea; NCS, non-convulsive seizures; PCCA, post-convulsive central apnea; PGES, post-ictal generalized electroencephalographic suppression; SpO2, peripheral capillary oxygen saturation; y, years; y.o, years old.
a
Analyzed only in GCS.