Fig. 2.

Loss of core TFs in the liver of patients with hepatitis or cirrhosis from various etiologies.

(A–B) Averages of the core or the second tier of TF transcript levels in the liver of patients with acetaminophen (APAP) intoxication (A), alcoholic hepatitis, hepatitis B virus-induced acute liver failure (HBV-ALF), or cirrhosis (B). Data were extracted from GSE74000 (quantile normalization), GSE28619 [Gene Chip Robust Multiarray Averaging (GC-RMA) normalization], GSE38941 (RMA normalization), and GSE25097 (RMA normalization). Gene expression changes were calculated relative to the respective healthy liver group included in each dataset.

Data information: For left of A and B, data were shown as box and whisker plot (significantly different as compared with healthy donors: *P < .05; **P < .01). Box, IQR; whiskers, 5–95 percentiles; and horizontal line within box, median. For middle and right of A and B, data represent the means ± SEM (significantly different as compared with healthy donors: *P < .05; **P < .01). Group sizes (n) are denoted in each figure.