Kidney injury in PCK rats fed diets with different sodium content. (a) Representative FITC-inulin clearance curves (left) and a summarizing graph showing GFR levels (right) obtained from PCK rats fed normal (0.4% NaCl, NS), high salt (4% NaCl, HS), and sodium-deficient (0.01% NaCl, SD) diets at the end of the experimental protocol. (b) Plasma BUN values in PCK rats fed a NS, HS and SD diets. N = 8 animals per group. Values were compared using a one-way ANOVA with a Tukey post-hoc test. In box plots, the box is SEM, the whiskers represent SD, and the line within the box shows median value.