Table 2.
Linear regression analysis of square root (ΔCBV%) along with time in mice.
| Region | NTL | NTL noscapine | arcAβ | arcAβ noscapine | |
|---|---|---|---|---|---|
| Motor cortex | Slope | 0.061 ± 0.002 | 0.066 ± 0.002 | 0.048 ± 0.001∗∗∗ | 0.057 ± 0.001## |
| Intercept | 2.178 ± 0.056 | 1.747 ± 0.047 | 1.4 ± 0.023 | 2.379 ± 0.037 | |
| R | 0.9243 | 0.9523 | 0.9773 | 0.9614 | |
| Sensory cortex | Slope | 0.064 ± 0.003 | 0.069 ± 0.004 | 0.038 ± 0.002∗∗∗ | 0.054 ± 0.003### |
| Intercept | 3.120 ± 0.087 | 3.383 ± 0.096 | 3.164 ± 0.058 | 2.989 ± 0.082 | |
| R | 0.8462 | 0.8399 | 0.8172 | 0.8162 | |
| Hippocampus | Slope | 0.045 ± 0.002 | 0.047 ± 0.002 | 0.050 ± 0.002 | 0.050 ± 0.002 |
| Intercept | 2.451 ± 0.047 | 2.127 ± 0.055 | 2.503 ± 0.048 | 2.959 ± 0.066 | |
| R | 0.9036 | 0.8816 | 0.917 | 0.8556 | |
| Thalamus | Slope | 0.042 ± 0.002 | 0.078 ± 0.003 | 0.049 ± 0.002 | 0.058 ± 0.002# |
| Intercept | 2.549 ± 0.063 | 2.669 ± 0.090 | 2.690 ± 0.044 | 2.731 ± 0.062 | |
| R | 0.8179 | 0.8829 | 0.9258 | 0.8999 | |
| Caudate nucleus | Slope | 0.054 ± 0.001 | 0.065 ± 0.001 | 0.059 ± 0.002 | 0.053 ± 0.002 |
| Intercept | 1.826 ± 0.032 | 1.327 ± 0.034 | 1.376 ± 0.043 | 1.848 ± 0.045 | |
| R | 0.9666 | 0.9744 | 0.9515 | 0.9334 | |
| Cerebellum | Slope | 0.035 ± 0.003 | 0.045 ± 0.003 | 0.035 ± 0.001 | 0.037 ± 0.002 |
| Intercept | 3.342 ± 0.075 | 2.946 ± 0.075 | 2.619 ± 0.033 | 2.429 ± 0.050 | |
| R | 0.6884 | 0.7877 | 0.9198 | 0.8486 | |
Data is shown as mean ± standard error of the mean; ∗∗∗p < 0.001 NTL vs. arcAβ, #p < 0.05, ##p < 0.01, and ###p < 0.001 arcAβ vs. arcA β-noscapine, two-way ANOVA with Tukey’s post hoc analysis; NTL (n = 8), NTL noscapine (n = 9), arcAβ (n = 9), arcAβ noscapine (n = 11).