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. 2019 Jan 24;4(2):e124575. doi: 10.1172/jci.insight.124575

Figure 4. Growth factor and chemokine downregulation distinguish MMF+ SLE patients from MMF– patients.

Figure 4

Proinflammatory soluble mediators (38 total) were measured by multiplex or ELISA. Overall trends in relative plasma soluble mediator levels are depicted by (A) radar plot using the group median Z scores. MMF– SLE patients (n = 10) are highlighted in blue and MMF+ SLE patients (n = 5) are in red. Soluble mediators are represented by dot plots and include (B) VEGF, (C) PDGF-BB, (D) SDF-1α/CXCL12, and (E) MIG/CXCL9. *P < 0.05, ***P < 0.001 by Kruskal-Wallis test with Dunn’s multiple comparisons test. Median ± standard deviation shown.