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. 2019 Feb 28;10:325. doi: 10.3389/fmicb.2019.00325

Table 2.

List of the auxotrophies of L. nagelii TMW 1.1827.

Name of amino acid Biosynthesis based on genome Absent enzyme of biosynthesis of amino acid pathway EC number
Alanine P None
Arginine P None
Asparagine P None
Aspartic acid P None
Cysteine P None
Glutamic acid P None
Glutamine P None
Glycine A Phosphoserine phosphatase Threonine aldolase EC 3.1.3.3EC 4.1.2.48
Serine A Phosphoserine phosphatase EC 3.1.3.3
Histidine P None
Leucine A Ketol-acid reductoisomerase Dihydroxy-acid dehydratase EC 1.1.1.86EC 4.2.1.9
Isoleucine A Citramalate synthaseKetol-acid reductoisomerase Dihydroxy-acid dehydratase EC 2.3.1.182 EC 1.1.1.86EC 4.2.1.9
Valine A Ketol-acid reductoisomerase Dihydroxy-acid dehydratase EC 1.1.1.86EC 4.2.1.9
Lysine P None
Methionine P None
Proline P None
Phenylalanine A Prephenate dehydratase Aromatic-amino-acid transaminase EC 4.2.1.51EC 2.6.1.57
Tryptophan A Anthranilate phosphoribosyltransferase Anthranilate synthase Indole-3-glycerol phosphate synthase Phosphoribosylanthranilate isomerase EC 2.4.2.18EC 4.1.3.27EC 4.1.1.48EC 5.3.1.24
Tyrosine P None
Threonine P None

P represents prototrophy for amino acids, while A represents auxotrophy for amino acids.