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. Author manuscript; available in PMC: 2019 Mar 12.
Published in final edited form as: J Med Chem. 2017 Apr 19;60(9):3814–3827. doi: 10.1021/acs.jmedchem.7b00018

Figure 3.

Figure 3

Results of 12.43 μg of α1(V)GlyΨ{PO2H-CH2}Val [mep14,32,Flp15,33] THPI/day treatment of EAE mice. (A, top left) Clinical score of treated (gray) and nontreated (black) animals. (B, top right) Percent weight change of treated (black) and nontreated (gray) animals. (C, bottom left) Average clinical score of treated and nontreated animals over the course of the experiment. (D, bottom right) Average percent weight change of treated and nontreated animals from induction to sacrifice. n = 5 per group, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. Statistical analysis was performed using a two-tailed Student t test.