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. 2019 Feb 28;15(2):e1007614. doi: 10.1371/journal.ppat.1007614

Fig 2. IL-21 is induced in the distal colon following infection with C. rodentium.

Fig 2

A. Cytokine ELISA of the indicated cytokines from supernatants of the ex-vivo organ culture of the colonic tissues from WT mice collected at different time-points p.i. (48 hr cultures). Data are Mean ± SEM from two or more experiments (n = 7 mice/time-point). Day 9 after infection is indicated by vertical dashed lines. B. The mRNA expression of indicated cytokines (IFN-γ, IL-17A, IL-21, and IL-22) and C. Cytokine receptors (IFN-γR, IL-17RA, IL-21R, and IL-22R) by immune cells in the LP and non-immune epithelial cells (IECs) in the pooled distal colon of WT mice (n = 25) 9 days after infection with C. rodentium analyzed by Nanostring.