Table 2 |.
Race-specific reduction in blood pressure (mm Hg) | White–black difference in response (mm Hg) | |||||
---|---|---|---|---|---|---|
Systolic | Diastolic | |||||
Author (year) | Whites | Blacks | Whites | Blacks | Systolic | Diastolic |
Krakoff (1990)21a | 16.5 (15.5, 17.5) | 18.5 (17.0, 20.0) | 12.9 (12.4, 13.4) | 13.9 (13.0, 14.8) | –2.0 (–3.8, –0.2) | –1.0 (–2.0, 0.0) |
Weir (1992)28 | 12.6 (8.4, 16.8) | 16.8 (11.2, 22.4) | 10.7 (9.6, 11.8) | 12.1 (10.2, 14.0) | –4.2 (–11.2, 2.8) | –1.4 (–3.6, 0.8) |
Black (1992)27b | not reported | not reported | 12.1 (10.5, 13.7) | 13.0 (10.8, 15.2) | not reported | –0.9 (–3.6, 1.8) |
Black (1992)27b | not reported | not reported | 13.6 (11.3, 15.9) | 11.4 (8.4, 14.4) | not reported | 2.2 (–1.6, 6.0) |
Materson (1993A)18c | 11.0 (8.1, 13.9) | 14.0 (10.8, 17.2) | 13.0 (11.4, 14.6) | 14.0 (12.4, 15.6) | –3.0 (–7.3, 1.3) | –1.0 (–3.3,1.3) |
Materson (1993B)18c | 12.0 (9.6, 14.4) | 15.0 (13.1, 16.9) | 14.0 (12.6, 15.4) | 15.0 (13.7, 16.3) | –3.0 (–6.1, 0.1) | –1.0 (–2.9, 0.9) |
Kloner (1996)29 | 15.8 (15.0, 16.6) | 18.2 (16.7, 19.7) | 12.5 (12.1, 12.9) | 12.6 (11.9, 13.3) | –2.4 (–4.1, –0.7) | –0.1 (–0.9, 0.7) |
Wright (2005)20a | 8.4 (7.9, 8.9) | 5.7 (5.0, 6.4) | 5.6 (5.3, 5.9) | 4.1 (3.7, 4.5) | 2.7 (1.8, 3.6) | 1.5 (1.0, 2.0) |
Values in parentheses are the 95% confidence intervals.
Not included in pooled analysis.
Same trial, two drug groups.
Same trial, A = participants <60 years old B=participants ≥60 years old.