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. Author manuscript; available in PMC: 2020 Mar 15.
Published in final edited form as: Acta Biomater. 2019 Jan 30;87:140–151. doi: 10.1016/j.actbio.2019.01.062

Figure 1. In vivo echocardiographic analysis of cardiac function.

Figure 1.

(A) Short-axis B-mode echocardiography images of the left ventricle at diastole showing expansion of the left ventricle 6 weeks post-injury. Quantification of end diastolic (B) and systolic (C) area show reduced ventricle size in nmECM-treated mice. Cardiac function, shown as fractional area change (D), fractional shortening (E), and ejection fraction (F), is not preserved in saline or amECM-treated mice but significantly improved in nmECM-treated mice. (n = 8 per group; *p < 0.05, **p < 0.01 relative to saline; #p < 0.05, ## p < 0.01 relative to amECM).