Table 1.
Patient and tumor characteristics
| Pat no. | Age | Gender | Histology | Location | TNM | GTV (cc) | Fract. no (dose, Gy) at rescan | Aeration change, % | GTV decrease, % |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 63 | M | SCC | Nasal cavity | T4N2M0 | 12.18 | 19 (38) | 4.7 | 11.7 |
| 2 | 31 | F | NK/TCL | Nasal cavity | T4N0M0 | 72.3 | 21 (42) | 3.1 | 6.8 |
| 3 | 25 | M | NPC | Nasopharynx | T4N1M0 | 93.56 | 21 (42) | 6.2 | 7.1 |
| 4 | 42 | M | NPC | Nasopharynx | T2N3M0 | 16.32 | 24 (48) | 14.7 | 28.1 |
| 5 | 59 | M | SCC | Right maxillary sinus | T4N0M0 | 54.72 | 25 (50) | 10.2 | 9.4 |
| 6 | 69 | M | NPC | Nasopharynx | T4N2M0 | 89.87 | 26 (52) | 5.0 | 14.6 |
| 7 | 57 | F | NPC | Nasopharynx | T4N2M0 | 50.66 | 27 (54) | 9.9 | 22.4 |
| 8 | 47 | M | SCC | Nasal cavity | T1N0M0 | 7.35 | 27 (54) | 2.1 | 18.9 |
| 9 | 56 | M | ACC | Sphenoid sinus | T4N0M0 | 38.8 | 27 (54) | 9.9 | 10.8 |
| 10 | 68 | M | SCC | Nasal cavity | T4N0M0 | 62.74 | 28 (56) | 2.2 | 21.6 |
| 11 | 67 | M | NPC | Nasopharynx | T3N1M0 | 109.15 | 28 (56) | 11.0 | 21.9 |
| 12 | 54 | F | MPNST | Right maxillary sinus | T2N1M0 | 0.34 | 29 (58) | 3.8 | 20.6 |
| 13 | 45 | M | SCC | Ethmoid sinus | T4N0M0 | 31.09 | 30 (60) | 8.0 | 43.9 |
| 14 | 49 | M | SCC | Ethmoid sinus | T4N2M0 | 124.55 | 30 (60) | 18.0 | 34.2 |
| Mean | 52.4 | 54.55 | 26 (52) | 7.6 | 19.0 | ||||
| Std | 13.4 | 39.49 | 3.5 (6.9) | 4.6 | 10.2 | ||||
| Median | 55.5 | 54.72 | 27 (54) | 7.1 | 19.8 | ||||
| Min | 25 | 0.34 | 19 (38) | 1.7 | 8.8 | ||||
| Max | 69 | 124.55 | 30 (60) | 18.0 | 43.9 |
Aeration change was calculated by measuring air content in the cavity that contained the tumor and the involved sinuses on pretreatment and repeat CT scans.
SCC, squamous cell carcinoma; NK/TL , NK/T cell lymphoma; NPC, nasopharyngeal carcinoma; ACC, adenoid cystic carcinoma; MPNST, malignant peripheral sheath tumor; TNM, Tumor Nodes Metastasis; GTV, gross tumor volume; cc, cubic centimeters.