Table II.

Body weight and water intake prior to and following treatment.

Measurement	Control	EG	EG + metformin
Body weight, g
0 week	194±11	198±12	193±11
2 weeks	253±18	249±17	241±19
4 weeks	324±19	335±18	313±17
6 weeks	392±20	388±22	363±21
8 weeks	461±25	457±27	405±24a,b
Fluid consumption, ml × day−1 × kg body weight−1
2 weeks	105±11	110±12	108±11
4 weeks	112±9	108±11	113±12
6 weeks	115±12	112±10	109±12
8 weeks	109±13	115±11	110±9

Data are presented as the mean ± standard deviation.

^aP<0.05, control, vs. EG + metformin;

^bP<0.05, EG, vs. EG + metformin. Statistical analyses were performed by one-way analysis of variance. EG, ethylene glycol.