Table IV.
Downregulation of epidermal barrier-associated genes following treatment with all-trans retinoic acid in HaCaT cells (n=1 per group;-fold change >2; P<0.05).
A, Intermediate filament
| |||
---|---|---|---|
GenBank accession no. | Gene name | Gene full name | Fold downregulation |
NM_181619 | KRTAP21-1 | Keratin associated protein 21-1 | 2.38 |
NM_033448 | KRT71 | Keratin 71 | 2.00 |
BC024292 | KRT5 | Keratin 5 | 2.22 |
| |||
B, Proteases and protease inhibitors | |||
| |||
GenBank accession no. | Gene name | Gene full name | Fold downregulation |
| |||
BC069417 | SERPINB7 | Serpin family B member 7 | 3.15 |
NM_000185 | SERPIND1 | Serpin family D member 1 | 2.36 |
NM_007173 | PRSS23 | Serine protease 23 | 4.13 |
NM_022046 | KLK14 | Kallikrein related peptidase 10 | 2.29 |
| |||
C, Tight junction | |||
| |||
GenBank accession no. | Gene name | Gene full name | Fold downregulation |
| |||
AK128686 | PDZD2 | PDZ domain containing 2 | 2.15 |