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. 2019 Feb 15;43(4):1789–1805. doi: 10.3892/ijmm.2019.4098

Table IV.

Downregulation of epidermal barrier-associated genes following treatment with all-trans retinoic acid in HaCaT cells (n=1 per group;-fold change >2; P<0.05).

A, Intermediate filament
GenBank accession no. Gene name Gene full name Fold downregulation
NM_181619 KRTAP21-1 Keratin associated protein 21-1 2.38
NM_033448 KRT71 Keratin 71 2.00
BC024292 KRT5 Keratin 5 2.22

B, Proteases and protease inhibitors

GenBank accession no. Gene name Gene full name Fold downregulation

BC069417 SERPINB7 Serpin family B member 7 3.15
NM_000185 SERPIND1 Serpin family D member 1 2.36
NM_007173 PRSS23 Serine protease 23 4.13
NM_022046 KLK14 Kallikrein related peptidase 10 2.29

C, Tight junction

GenBank accession no. Gene name Gene full name Fold downregulation

AK128686 PDZD2 PDZ domain containing 2 2.15
HHS Vulnerability Disclosure