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. Author manuscript; available in PMC: 2020 Apr 15.
Published in final edited form as: Eur J Pharmacol. 2019 Jan 30;849:84–95. doi: 10.1016/j.ejphar.2019.01.051

Fig. 1. Sevoflurane attenuated oxygen-glucose deprivation (OGD)-induced cell injury and chloroquine enhanced the injury.

Fig. 1.

Neuron-like cells were subjected to 1 h OGD followed with a 20 h simulated reperfusion. A: Cells were exposed to various concentrations of sevoflurane for 1 h immediately after the onset of simulated reperfusion. Results are means ± S.E.M. (n = 18). B: Chloroquine was added just before the OGD and was present till the cells were harvested for LDH release assay. Sevoflurane at 2% was used in this experiment. Results are means ± S.E.M. (n = 9). * P < 0.05 compared to control. ^ P < 0.05 compared to OGD group. # P < 0.05 compared with the corresponding condition without chloroquine. OGD: oxygen-glucose deprivation; Sevo: 2% sevoflurane