Figure 2.

Average ${\langle }^{15}\text{N-}{R}_2^{\text{B}}\rangle$ values obtained from a fit of the ¹⁵N-DEST/ΔR₂ data of htt^NT in the presence of SUVs (600 MHz; 10 °C) to a two-state exchange model (y-axis), plotted versus the population of SUV-bound htt^NT (p_B) which was fixed in the fit (x-axis). For a particle of 31 nm in diameter, one can estimate a range of 4.5−9 μs for the rotational correlation time, corresponding to ⟨¹⁵N-$R_2^{\text{B}}$⟩ values of 2000−4000 s⁻¹. The bound population p_B for this range of ⟨¹⁵N‑$R_2^{\text{B}}$⟩ values spans ∼9−4.5% (enclosed in the blue box).