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. Author manuscript; available in PMC: 2019 Mar 13.
Published in final edited form as: Pharmacogenomics J. 2018 Sep 12;19(3):305–314. doi: 10.1038/s41397-018-0043-3

Figure 4. G6PD genotype in females does not correspond well with phenotype.

Figure 4.

Of 279 females, 268 had normal and 11 had deficient activity. No female was homozygous for a Class I-III allele, and 10/268 (3.7%) of those with normal activity and 2/11 (18%) of those with deficient activity carried one Class I-III allele. Of the 12 “variable” females (those heterozygous for a Class I-III allele), only 2 had deficient activity (16.7%). 258 out of 267 patients with only Class IV alleles had normal G6PD activity, resulting in a negative predictive value of 96.6% (93.5–98.3%).