Table 1.
Mouse orthologs of human X-Y pair and PAR1 genes.
| Chromosomal location |
|||
|---|---|---|---|
| Human Gene | Human | Mousea | |
| Ancestral X-Y pair genes | SOX3/SRY | X/Y | X/Y |
| ZFX/ZFY | X/Y | X/Y | |
| DDX3X/Y | X/Y | X/Yb | |
| KDM6A/UTY | X/Y | X/Yb | |
| KDM5C/D | X/Y | X/Yb | |
| USP9X/Y | X/Y | X/Y | |
| EIF1AX/Y | X/Y | X/18c | |
| RPS4X/Y | X/Y | X/6c | |
| AMELX/Y | X/Y | X/- | |
| TXLNG/Y | X/Y | X/- | |
| TMSB4X/Y | X/Y | X/- | |
| NLGN4X/Y | X/Y | X/Y (PAR) | |
| TBL1X/Y | X/Y | X/- | |
| PRKX/Y | X/Y | X/- | |
| PAR genes | PLCXD1 | X/Y (PAR1) | 5 |
| GTPBP6 | X/Y (PAR1) | 5d | |
| PPP2R3B | X/Y (PAR1) | 9 | |
| SHOX | X/Y (PAR1) | -e | |
| CRLF2 | X/Y (PAR1) | 5 | |
| CSF2RA | X/Y (PAR1) | 19f | |
| IL3RA | X/Y (PAR1) | 14g | |
| SLC25A6 | X/Y (PAR1) | -g | |
| ASMTL | X/Y (PAR1) | - | |
| P2RY8 | X/Y (PAR1) | - | |
| AKAP17A | X/Y (PAR1) | X/Y (PAR) | |
| ASMT | X/Y (PAR1) | X/Y (PAR) | |
| DHRSX | X/Y (PAR1) | 4d | |
| ZBED1 | X/Y (PAR1) | -d | |
| CD99 | X/Y (PAR1) | 4h | |
PAR = pseudoautosomal region
a
For X-Y pairs, presence or absence of the Y copy in mouse is confirmed in (Soh et al., 2014).
b
X homolog expressed from both X chromosomes in human and mouse (Berletch et al., 2015; Yang, Babak, Shendure, & Disteche, 2010).
e
Human and mouse have a paralagous gene, SHOX2, on chr3 (Rao et al., 1997).