Table 3.
Functional Annotations in Genes Unique to Entamoeba histolytica, Entamoeba dispar, Entamoeba invadens, or Entamoeba moshkovskii
| Number of Families with Function | Number of Genes within Families | Family Function |
|---|---|---|
| E. histolytica | ||
| 6 | 22 | BspA family |
| 4 | 18 | Surface antigen ariel1 |
| 2 | 12 | AIG1 family |
| 2 | 12 | Mucins |
| 2 | 7 | Cylicin-2 |
| 2 | 7 | Cysteine protease (inc. five pseudogenes) |
| 1 | 6 | Acetyltransferase |
| E. dispar | ||
| 1 | 13 | AIG1 family |
| 2 | 5 | Heat shock protein |
| E. invadens | ||
| 46 | 214 | Serine/threonine/tyrosine kinase |
| 9 | 34 | Ras family GTPase |
| 2 | 32 | Ribonuclease |
| 8 | 27 | Heat shock protein |
| 1 | 21 | Cylicin |
| 2 | 21 | Myosin |
| 2 | 19 | Glutamine/asparagine-rich protein pqn-25 |
| 5 | 16 | Actin |
| 1 | 15 | Thioredoxin |
| 1 | 12 | Profilin |
| 1 | 11 | Capsular polysaccharide phosphotransferase |
| 2 | 11 | DNA double-strand break repair Rad50 ATPase |
| 1 | 9 | Embryonic protein DC-8 |
| 3 | 8 | Serine/threonine protein phosphatase |
| 1 | 8 | Tropomyosin alpha-1 chain |
| 2 | 7 | ADP ribosylation factor |
| 2 | 7 | Cysteine protease |
| 1 | 7 | Elongation factor 1-alpha |
| 1 | 7 | Furin |
| 2 | 6 | Actophorin |
| 1 | 6 | Gal/GalNAc lectin light subunit |
| 1 | 6 | Nitrogen fixation protein nifU |
| 1 | 5 | Calcium-binding protein/Caltractin/Centrin-1 |
| 2 | 5 | Chaperone Clpb |
| 1 | 5 | DNA repair and recombination protein rad52 |
| 1 | 5 | GRIP domain-containing protein RUD3 |
| 2 | 5 | Serpin (serine protease inhibitor) |
| 1 | 5 | Vacuolar protein sorting-associated protein |
| 40 | 753 | BspA like family |
| E. moshkovskii | ||
| 80 | 538 | Serine/threonine/tyrosine/protein kinase |
| 10 | 58 | Ras family GTPase |
| 5 | 53 | Transposable element/transposase |
| 4 | 46 | Tigger transposable element-derived protein |
| 9 | 36 | Actin |
| 8 | 26 | Heat shock protein |
| 4 | 17 | Leukocyte elastase inhibitor |
| 1 | 14 | Large xylosyl- and glucuronyltransferase 2 isoform X1 |
| 2 | 13 | GNAT family N-acetyltransferase |
| 1 | 12 | Enhancer binding protein-2 |
| 4 | 11 | DNA double-strand break repair Rad50 ATPase |
| 1 | 10 | TonB-dependent siderophore receptor |
| 1 | 9 | Methionine–tRNA ligase |
| 1 | 9 | Tandem lipoprotein |
| 2 | 8 | DEAD/DEAH box helicase |
| 2 | 8 | Reverse transcriptase |
| 1 | 8 | Chaperone |
| 3 | 7 | Methyltransferase (various) |
| 3 | 7 | Cysteine proteinase |
| 1 | 7 | Putative AC transposase |
| 3 | 6 | DNA mismatch repair protein MsH2 |
| 2 | 6 | piggyBac transposable element-derived protein |
| 1 | 6 | Polyphosphate:AMP phosphotransferase |
| 1 | 6 | Primary-amine oxidase |
| 1 | 6 | Surface antigen-like protein |
| 1 | 6 | Translation elongation factor |
| 1 | 6 | Type VI secretion system tip protein VgrG |
| 1 | 6 | Site-specific tyrosine recombinase XerC |
| 2 | 5 | Chaperone protein DNAK |
| 1 | 5 | Diaminobutyrate-2-oxoglutarate transaminase |
| 1 | 5 | Response regulator |