Table 2. List of registered clinical trials involving Selinexor in various malignancies (44).
# | NCT number | Conditions |
---|---|---|
1 | NCT03193437 | Thymoma |
2 | NCT03095612 | NSCLC |
3 | NCT03147885 | Lymphoma (various types) |
4 | NCT02606461 | Liposarcoma |
5 | NCT02249091 | AML |
6 | NCT01986348 | Glioblastoma, glioma |
7 | NCT02402764 | Breast cancer |
8 | NCT02227251 | DLBCL |
9 | NCT02250885 | Neuroendocrine carcinoma |
10 | NCT02025985 | Ovarian, endometrial, cervical, breast cancer |
11 | NCT02530476 | Leukemia |
12 | NCT02403310 | Leukemia |
13 | NCT02471911 | DLBCL |
14 | NCT02336815 | MM |
15 | NCT02389543 | MM |
16 | NCT02323880 | Childhood CNS/solid neoplasm, lymphoma |
17 | NCT03466827 | Thymoma |
18 | NCT02078349 | Solid tumors |
19 | NCT02485535 | AML, MDS |
20 | NCT02283359 | Esophageal, gastric cancer |
21 | NCT02215161 | Prostate cancer |
22 | NCT02831686 | MM |
23 | NCT02573363 | AML |
24 | NCT02199665 | MM |
25 | NCT02314247 | T-cell lymphoma |
26 | NCT02835222 | AML |
27 | NCT02138786 | Richter’s transformation |
28 | NCT02228525 | MDS |
29 | NCT02120222 | Melanoma |
30 | NCT02091245 | Leukemia |
31 | NCT02741388 | B-cell lymphoma |
32 | NCT02212561 | AML, ALL, MDS, MPAL |
33 | NCT03042819 | Soft tissue sarcoma |
34 | NCT02213133 | Squamous cell carcinoma |
35 | NCT02780609 | MM |
36 | NCT02431351 | MDS |
37 | NCT02384850 | Colorectal neoplasm |
38 | NCT02186834 | MM |
39 | NCT02299518 | AML |
40 | NCT01607905 | Solid tumor |
41 | NCT02351505 | SCLC |
42 | NCT02343042 | MM |
43 | NCT02628704 | MM |
44 | NCT03555422 | Endometrial cancer |
45 | NCT02146833 | Prostate cancer |
46 | NCT03212937 | T-cell lymphoma |
47 | NCT02536495 | Squamous cell lung carcinoma |
48 | NCT02269293 | Ovarian, endometrial cancer |
49 | NCT02137356 | Rectal neoplasms |
50 | NCT02093403 | AML |
51 | NCT02303392 | Leukemia, lymphoma |
52 | NCT01607892 | Hematological malignancies |
53 | NCT03071276 | AML |
54 | NCT02178436 | Pancreatic cancer |
55 | NCT03110562 | MM |
56 | NCT02088541 | AML |
57 | NCT02416908 | AML |
58 | NCT02069730 | Salivary gland cancer |
59 | NCT01896505 | Sarcoma |
60 | NCT02419495 | Advanced cancers |
NSCLC, non-small cell lung cancer; AML, acute myeloid leukemia; DLBCL, diffuse large B-cell lymphoma; MM, multiple myeloma; CNS, central nervous system; MDS, myelodysplastic syndrome; ALL, acute lymphoblastic leukemia; MPAL, mixed phenotype acute leukemia; SCLC, small cell lung cancer.