Table 3.

Clusters of between-group differences in within-network connectivity.

	ROI	Voxels	MAX X (mm)	MAX Y (mm)	MAX Z (mm)	p-Value peak
HC > PT
DMN	MTG.r/TL.r	367	60	−22	−10	0.030
	MFG.r	348	54	34	20	0.034
	PCC.r/PL.r	141	6	−54	10	0.029
CER	CER.r	2478	48	−50	−28	0.048
	CER.l	1254	−36	−40	−34	0.050
FP.l	SPL.l/PL.l	840	−32	−48	48	0.048
	MFG.l/FL.l	89	−44	14	38	0.050
FP.r	FL.r	460	48	50	10	0.029
	PPC.r	267	48	−56	28	0.048
TEMP	TL.r/pHiPPa.r	791	32	−8	−32	0.042
HC < PT
VISmed	LgG.l/TOF.l	286	−28	−48	−6	0.028
	OFG.r/OL.r	141	26	−68	−10	0.038
	OL.l/PL.l	31	−16	−68	18	0.041
VISocc	OFG.l/OL.l	283	−16	−80	−14	0.017
	LOC.l/OL.l	133	−28	−94	−2	0.042
SMN	PRG.l/pCg.l	2959	−12	−32	40	0.010
	SMC	50	−6	−22	60	0.044
EXE	FL.r/SFG.r	467	26	44	14	0.030
	FL.l/MFG.l	463	−32	44	20	0.038
	PAC/ACC	30	0	46	−2	0.044
TEMP	TL.l/pHiPPa.l	1284	−24	−4	−22	0.041

The statistical results identified by the permutation testing on the dual regression output are reported for each resting-state network (p < 0.05, FWE-corrected with TFCE). In particular, clusters of within-network decreased connectivity in patients compared to controls (HC > PT) as well as those of increased connectivity (HC < PT) were identified. MTG, middle temporal gyrus; TL, temporal lobe; MFG, middle frontal gyrus; PCC, posterior cingulate cortex; PL, posterior lobe; CER, cerebellum; SPL, superior parietal lobe; FL, frontal lobe; PPC, posterior parietal cortex; pHIPP, parahippocampus; LgG, lingual gyrus; TOF, Temporooccipital fusiform gyrus; OFG, orbitofrontal gyrus; OL, occipital lobe; LOC, Lateral occipital lobe; PRG, precentral gyrus; pCg, postcentral gyrus; SMC, supplementary motor cortex; SFG, superior frontal gyrus; PAC, paracingulate gyrus; ACC, anterior cingulate cortex; l, left; r, right.