Table 1.
KEGG pathways enriched among under and overrepresented proteins upon infection of THP-1 macrophages with R. conorii.
| ID | Pathway description | Count in gene set | False discovery rate |
|---|---|---|---|
| KEGG Pathways | |||
| R. conorii-Infected Cells—Proteins With Reduced Abundance | |||
| 1200 | Carbon metabolism | 13 | 8.61E-09 |
| 1100 | Metabolic pathways | 38 | 1.26E-08 |
| 30 | Pentose phosphate pathway | 7 | 4.90E-07 |
| 10 | Glycolysis/Gluconeogenesis | 9 | 5.46E-07 |
| 3050 | Proteasome | 8 | 5.46E-07 |
| 1230 | Biosynthesis of amino acids | 9 | 1.57E-06 |
| 5130 | Pathogenic Escherichia coli infection | 8 | 1.88E-06 |
| 5203 | Viral carcinogenesis | 12 | 1.08E-05 |
| 480 | Glutathione metabolism | 7 | 1.76E-05 |
| R. conorii-Infected Cells—Proteins With Enriched Abundance | |||
| 4141 | Protein processing in endoplasmic reticulum | 23 | 3.69E-19 |
| 5012 | Parkinson's disease | 16 | 9.80E-12 |
| 1100 | Metabolic pathways | 36 | 1.40E-09 |
| 5016 | Huntington s disease | 15 | 3.68E-09 |
| 20 | Citrate cycle (TCA cycle) | 8 | 3.72E-09 |
| 1200 | Carbon metabolism | 12 | 3.72E-09 |
| 5010 | Alzheimer s disease | 12 | 7.80E-07 |
| 510 | N-Glycan biosynthesis | 7 | 6.07E-06 |
| 4260 | Cardiac muscle contraction | 8 | 8.43E-06 |
| 3060 | Protein export | 5 | 2.99E-05 |
| 190 | Oxidative phosphorylation | 9 | 4.95E-05 |