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. 2019 Mar 6;10:418. doi: 10.3389/fimmu.2019.00418

Table 3.

Cytokine production and the proliferative responses of splenocytes from BALB/c mice immunized with PBS, pVAX1, pVAX1-GRA24, or blank control.

Groups (n = 5) Cytokine production (pg/ml) Proliferation (SI)a
IFN-γ IL-12 IL-4 IL-10
Blank control 39.56 ± 4.86 35.29 ± 4.21 43.21 ± 3.69 25.69 ± 2.39 0.95 ± 0.13
PBS 37.59 ± 3.98 39.15 ± 4.26 39.65 ± 4.12 27.19 ± 3.78 1.03 ± 0.14
pVAX1 39.74 ± 4.56 42.11 ± 3.98 41.59 ± 3.59 28.13 ± 4.12 0.99 ± 0.17
pVAX1-GRA24 535.59 ± 59.78* 325.18 ± 37.59* 223.89 ± 30.19* 201.23 ± 29.15* 2.19 ± 0.13*
a

SI, stimulation index.

*

p < 0.05 compared with the control groups.