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. 2019 Mar 6;10:392. doi: 10.3389/fimmu.2019.00392

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Copyright © 2019 Kordon, Abdelhamed, Ahmed, Baumgartner, Karsi and Pinchuk.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Changes in the expression of IFN-γ (A), MHC class II (B), CD4-1 (C), CD4-2 (D), CD8-α (E), CD8-β (F), IL-8 (G), IL-1β (H), and TNF-α (I) genes in the spleen of catfish challenged with E. ictaluri LAV and WT strains. Data are presented as fold difference of gene expression compared with values obtained for control uninfected cells. Samples were analyzed in triplicates from a pull of spleen of six fish and presented as mean ± SD. ^*Indicates significant differences compared to uninfected control (p < 0.05). ^abc Indicates differences within each time point (P < 0.05).