Table 2.

LESION results of imaging targets were modeled separately using logistic regression across 3 steps: univariate model of sex and target, an a priori multivariate model including sex, age, NIHSS, and onset time (Model 2), then a stepwise inclusion process of all potential confounders for possible adjustment

	Model 1: univariate differences		Model 2 (sex, age, NIHSS, onset time)		Confounders identified by 10% change in effect from significant P‐values in Table 1	Model 3: Stepwise adjusted for additional confounders
	Effect size of sex difference (OR)	P‐value	Effect size of sex difference (OR)	P‐value		Effect size of sex difference (OR)	P‐value
Any arterial target	1.59	<0.001	1.60	0.001	None
MCA occlusion (M1/M2)	1.44	0.007	1.51	0.005	Platelets	1.30	0.132
Endovascular target (ICA/M1)	1.45	0.013	1.32	0.088	None
Perfusion target	1.46	0.017	1.42	0.040	PTT, BMI	1.87	0.045
Perfusion‐diffusion mismatch	1.36	0.022	1.36	0.034	None

All imaging targets were predicted by women with platelets, PTT and BMI being confounding factors for MCA and perfusion targets, respectively. No mediation or interactions were found.