Comparison 4. Mediterranean dietary intervention versus another dietary intervention for secondary prevention.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Non‐fatal MI	1		Risk Ratio (Random, 95% CI)	0.47 [0.28, 0.79]
2 Non‐fatal MI (sensitivity analysis without Singh studies)	0		Risk Ratio (Random, 95% CI)	0.0 [0.0, 0.0]
3 Fatal MI	2		Risk Ratio (Random, 95% CI)	0.66 [0.61, 0.71]
4 Fatal MI (sensitivity analysis without Singh studies)	0		Risk Ratio (Random, 95% CI)	0.0 [0.0, 0.0]
5 Sudden cardiac death	2		Risk Ratio (Random, 95% CI)	0.48 [0.37, 0.63]
6 Sudden cardiac death (sensitivity analysis without Singh studies)	0		Risk Ratio (Random, 95% CI)	0.0 [0.0, 0.0]
7 Total cardiac endpoints (fatal and non‐fatal MI, sudden cardiac death)	2		Risk Ratio (Random, 95% CI)	0.59 [0.44, 0.80]
8 Total cardiac endpoints (fatal and non‐fatal MI, sudden cardiac death) (sensitivity analysis without Singh studies)	0		Risk Ratio (Random, 95% CI)	0.0 [0.0, 0.0]
9 Total mortality	1		Risk Ratio (Random, 95% CI)	0.59 [0.51, 0.68]
10 Total mortality (sensitivity analysis without Singh studies)	0		Risk Ratio (Random, 95% CI)	0.0 [0.0, 0.0]
11 CVD mortality	1		Risk Ratio (Random, 95% CI)	0.50 [0.42, 0.60]
12 CVD mortality (sensitivity analysis without Singh studies)	0		Risk Ratio (Random, 95% CI)	0.0 [0.0, 0.0]
13 Total cardiac endpoints (all‐cause and cardiac deaths, MI, hospital admissions for heart failure, unstable angina or stroke, unadjusted)	1	101	Risk Ratio (M‐H, Random, 95% CI)	0.98 [0.40, 2.41]
14 Total cholesterol (mmol/L), change from baseline	2	1283	Mean Difference (IV, Random, 95% CI)	‐0.50 [‐0.61, ‐0.39]
15 Total cholesterol (mmol/L), change from baseline (sensitivity analysis without Singh studies)	0	0	Mean Difference (IV, Random, 95% CI)	0.0 [0.0, 0.0]
16 LDL cholesterol (mmol/L), change from baseline	3		Mean Difference (IV, Random, 95% CI)	Totals not selected
17 LDL cholesterol (mmol/L), change from baseline (sensitivity analysis without Singh studies)	1	71	Mean Difference (IV, Random, 95% CI)	0.08 [‐0.26, 0.42]
18 HDL cholesterol (mmol/L), change from baseline	3	1354	Mean Difference (IV, Random, 95% CI)	0.06 [‐0.01, 0.12]
19 HDL cholesterol (mmol/L), change from baseline (sensitivity analysis without Singh studies)	1	71	Mean Difference (IV, Random, 95% CI)	‐0.05 [‐0.17, 0.06]
20 Triglycerides (mmol/L), change from baseline	3		Mean Difference (IV, Random, 95% CI)	Totals not selected
21 Triglycerides (mmol/L), change from baseline (sensitivity analysis without Singh studies)	1	71	Mean Difference (IV, Random, 95% CI)	0.46 [‐0.24, 1.16]
22 Systolic blood pressure (mmHg), change from baseline	4		Mean Difference (IV, Random, 95% CI)	Totals not selected
23 Systolic blood pressure (mmHg), change from baseline (sensitivity analysis without Singh studies)	2	150	Mean Difference (IV, Random, 95% CI)	1.76 [‐2.80, 6.33]
24 Diastolic blood pressure (mmHg), change from baseline	4		Mean Difference (IV, Random, 95% CI)	Totals not selected
25 Diastolic blood pressure (mmHg), change from baseline (sensitivity analysis without Singh studies)	2	150	Mean Difference (IV, Random, 95% CI)	0.98 [‐1.97, 3.93]