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. 2019 Mar 12;9:4197. doi: 10.1038/s41598-019-40875-1

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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RMSF contributed by the first three principal components. The fractional contribution of each PC to the overall variance is shown in the top right part of each graph. Interpolated structures obtained by displacements along each vector are displayed within each plot. Blue indicates overlapping regions with little or no motion. Red areas represent mobile regions. The secondary structure elements are given at the lower margin of the plots and colored according to the figure caption.