Table 2.
Top 10 canonical Ingenuity pathways for the differentially expressed proteins at BCP-ALL relapse.
| Gene | P-value | Molecules (Proteins) |
|---|---|---|
| Glycolysis I | 0.000227 | ALDOA, ALDOC, GPI, PGAM1, PGK1, PKM |
| Gluconeogenesis I | 0.000227 | ALDOA, ALDOC, GPI, MDH1, PGAM1, PGK1 |
| Pentose Phosphate Pathway | 0.001333 | G6PD, PGD, TALDO1, TKT |
| CDP-diacylglycerol Biosynthesis I | 0.005917 | AGPAT5, CDS2, LPCAT3, MBOAT7 |
| Phosphatidylglycerol Biosynthesis II (Non-plastidic) | 0.006806 | AGPAT5, CDS2, LPCAT3, MBOAT7 |
| EIF2 Signaling | 0.009853 | RPL14, RPL17, RPL23A, RPL3, RPL36, RPL7, RPL8, RPS17 |
| Sirtuin Signaling Pathway | 0.010153 | ACLY, G6PD, H1FX, LDHB, NAMPT, PCK2, PGAM1, PGK1, TIMM9 |
| Adenine and Adenosine Salvage I | 0.010567 | APRT, PNP |
| Antigen Presentation Pathway | 0.013300 | HLA-DRA, HLA-DRB1, TAP2, TAPBP |
| Pentose Phosphate Pathway (Oxidative Branch) | 0.039164 | G6PD, PGD |