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MHV68-EGFP infection, but not wildtype MHV68 infection, induces slight peri-insulitis in some islets of MIP-TF mice. (A) Representative image of peri-insulitis in a MHV68-EGFP-infected MIP-TF mouse at day 21 post-infection. White bar indicates 100 μm. (B) Insulitis was scored at 21 days-post-infection on a scale of 0–3, as described in Methods. Black bar = MHV68-EGFP infected (n = 8). Insulitis in wildtype MHV68-infected mice was at base-line (n = 5).
