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. 2019 Mar 12;9:4274. doi: 10.1038/s41598-019-40850-w

Table 1.

Characteristics of ADHD children and healthy controls.

ADHD Controls p-value
Gender, N(%) 0.200
Male 141(83.93) 183(78.54)
Female 27(16.07) 50(21.46)
Age(year), Mean (SD) 8.55(1.62) 8.60(1.76) 0.760
Family history of neural system diseases, N(%) 0.570
  Yes 2(1.19) 1(0.43)
  No and Unknown 166(98.81) 232(99.57)
Parental marital status, N(%) 0.245
  Marries 148(88.10) 214(91.85)
  Single, separated, divorced or widowed 16(11.90) 14(8.15)
Pregnancy age of mother(y), mean(S.D.) 26.54(4.19) 27.57(5.11) 0.028
Low birth weight(<2500 g), N(%) 12(7.14) 17(7.30) 0.953
Preterm birth(<37 weeks), N(%) 17(10.12) 21(9.01) 0.695
Delivery mode, N(%) 0.254
  Cesarean section 50(29.76) 57(24.47)
  Vaginal delivery 118(70.24) 176(75.54)
  Breast feeding, N(%) 101(60.11) 146(62.66) 0.161
Intelligence Quotient, mean (S.D.) 98.50(12.07) 98.90(13.02) 0.730
SNAP-IV rating scales, mean(S.D)
  Inattention scores 1.95(0.49) 0.64(0.42) <0.001
  Hyperactivity scores 1.40(0.73) 0.42(0.36) <0.001
  Oppositional defiant scores(ODD) 1.04(0.69) 0.45(0.42) <0.001
CBCL scales, mean(S.D) 44.87(25.07) 18.91(18.89) <0.001
Blood lead (ug/dL), mean (S.D.) 3.58(1.59) 3.26(1.69) 0.846
  Male 3.65(1.61) 3.57(1.79) 0.345
  Female 3.64(1.17) 3.63(1.16) 0.722
  Inattention 3.45(1.58) 3.36(1.69) 0.345
  Hyperactivity/impulsivity 3.64(1.58) 3.63(1.71) 0.721
  ADHD-ODD(N = 40) 3.71(1.59) 3.63(1.70) 0.111
Prenatal tobacco exposure, N(%) 58(34.52) 53(22.74) 0.010
Postnatal tobacco exposure, N(%) 53(31.54) 55(23.61) 0.087
Drinking during pregnancy, N(%) 4(2.4) 6(2.6) 0.896

p-value was calculated using chi-squared test if percentages are compared, or t test if means are compared.